What exactly is NMN?
NMN is short for nicotinamide mononucleotide, a naturally sourced molecule contained in all species. About the molecular level, this is a ribonucleotide, a basic structural unit with the nucleic acid RNA. It is made up of nicotinamide group, a ribose, and a phosphate group.
NMN is often a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that could be useful in slowing down some elements of aging. NAD+ serves many critical functions in our cells, like electron transport, cell signaling, and DNA repair.
Accumulating evidence suggests that as our bodies age, our amounts of NAD+ decline, increasing our likelihood of age-related diseases.
This is when the NAD+ precursor NMN also comes in. Some researchers believe when we can restore that lost NAD+, we could not only slow aging but additionally delay various age-related diseases. Whether restoring NAD+ metabolism in humans will decelerate aging or support healthy longevity is still an unanswered question, although the animal information is promising.
What foods contain NMN?
NMN is found naturally in foods for example avocado, broccoli, cabbage, cucumber, and edamame. Here is how much NMN is found in some common foods.
While such foods are rich in nutrition, dietary NMN supplements are offered also. These supplements typically come in doses of between 100 – 500 mg, although an optimal dose has yet to be determined in people.
Fasting and caloric restriction also seem to increase NAD+ levels and improve the activity of sirtuins, aka the longevity genes. It is suggested their activity depends on the presence of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and it generally seems to decelerate aging.
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