What exactly is NMN?
NMN is brief for nicotinamide mononucleotide, a natural molecule present in all species. Around the molecular level, it’s a ribonucleotide, a fundamental structural unit from the nucleic acid RNA. It includes a nicotinamide group, a ribose, as well as a phosphate group.
NMN is really a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that may be beneficial in slowing some areas of aging. NAD+ serves many critical functions within our cells, like electron transport, cell signaling, and DNA repair.
Accumulating evidence suggests that as we grow older, our amounts of NAD+ decline, increasing our risk of age-related diseases.
This is when the NAD+ precursor NMN also comes in. Some researchers believe that when we can restore that lost NAD+, we’re able to not merely decrease aging and also delay various age-related diseases. Whether or not restoring NAD+ metabolism in humans will decelerate aging or support healthy longevity is still an unanswered question, the animal data is promising.
What foods contain NMN?
NMN can be found naturally in foods including avocado, broccoli, cabbage, cucumber, and edamame. This is one way much NMN can be found in some common foods.
While most of these foods are loaded with nutrition, dietary NMN supplements are also available. These supplements typically come in doses which can be between 100 – 500 mg, although an optimal dose has not yet been determined in people.
Fasting and caloric restriction also seem to increase NAD+ levels and boost the activity of sirtuins, aka the longevity genes. It’s advocated their activity relies on a good NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and yes it appears to decelerate aging.
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